Thus, the hypothesis focused primarily on neutrophil and neutrophil elastase as the primary cell and enzyme responsible for copd. Moreover, the benefit of ellagic acid on cytoprotection, resulting from its antioxidant properties was documented. Neutrophil elastase (elane) mutations are the most common cause of cyclic (cyn) and congenital neutropenia (scn), two autosomal dominant disorders causing recurrent infections due to impaired neutrophil production.
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Discover the latest articles, books and news in related subjects, suggested using machine learning. We reviewed and included 132 articles conceptualizing neutrophil elastase activity and known inhibitors. D its inhibition effi ciency on elastase was studied by spectroscopic methods.
In recent years regulation of the enzymatic activity of human neutrophil elastase (hne) has been the main focus of investigation, due to its potential therapeutic application in medicinal field.
